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Week 2: After two weeks of buprenoprhine withdrawal, the pain and discomfort of acute withdrawal may not be as severe but you still experience aches.

Onset of withdrawal from buprenorphine usually occurs 48 hours after the last dose, peaks around the third day and lasts for up to ten days.

People going through buprenorphine PAWS manifest long lasting changes in the brain as a result of long term use.

These changes are slower to reverse and can persist for many months, depending on the frequency and amount of past dosing.

Week 3-4: After three to four week mark, most of the physical withdrawal symptoms will be gone, however you will intense drug cravings may be present for those addicted to buprenorphine. This time is very important, as you will be very vulnerable to relapse.